As ‘CSI’ Turns 25, Creator Anthony Zuiker Looks Back on Adding Sara, Tarantino’s ‘Grave Danger’ & More

Twenty-five years ago, CSI changed the way that TV viewers and the world looked at forensics.

Created by Anthony Zuiker, CSI turned the focus to using science to solve crimes, and after the premiere aired on October 6, 2000, well, the rest was history. Over its 15-year-run, the cast included William Petersen, Marg Helgenberger, Jorja Fox, George Eads, Gary Dourdan, Paul Guilfoyle, Eric Szmanda, and Robert David Hall, and included quite a few memorable guest stars and episodes.